---
title: Rewriting Rare Disease R&D with Foundation Models
description: RAREcast interview with Jean-Philippe Vert about the potential to transform rare disease drug development with foundation models.
---

[Skip to content](https://resources.bioptimus.com/rewriting-rare-disease-rd-with-foundation-models#main-content)

English

Show submenu for translations

![Bioptimus logo\_Logo Black](https://resources.bioptimus.com/hs-fs/hubfs/Bioptimus%20logo_Logo%20Black.png?width=500&height=188&name=Bioptimus%20logo_Logo%20Black.png)

- Home
- Products
- Resources
- Company

Open main navigation

Close main navigation

- Home
- Products
- Resources
- Company
- English
  
  Show submenu for translations
- Contact us

 Contact us

 How can we help you?

- There are no suggestions because the search field is empty.

1. [Resources](https://resources.bioptimus.com/?hsLang=en)
2. [Videos, Podcasts & Webinars](https://resources.bioptimus.com/videos-podcasts-webinars?hsLang=en)

# Rewriting Rare Disease R&D with Foundation Models

## Podcast

Drug development has long been a costly, trial-and-error effort, with nine out of ten clinical programs failing despite major scientific advances. One reason is that biological information remains fragmented in silos, and traditional R&D approaches often rely on narrow, task-specific datasets. Bioptimus aims to change this by using AI to build a foundation model that integrates multimodal, multiscale biological data into a single body of knowledge. The approach has particular promise for rare diseases, where patient numbers and data are scarce, preclinical models are poor, and development economics are challenging. We spoke with Jean-Philippe Vert, co-founder and CEO of Bioptimus, about the inherent messiness of biology, the potential to transform rare disease drug development with a foundation model, and how uncovering similarities between conditions could enable repurposing of existing drugs.

Listen to the full conversation: [RAREcast](https://open.spotify.com/episode/1w4D7qVRUM6zCMdH6mbW4V?si=1gyQdrtFQoabz01OIJWO7A&utm_campaign=307601614-Brand+Awareness&utm_content=535525595&utm_medium=social&utm_source=linkedin&hss_channel=lcp-100658107&nd=1&dlsi=0c75e126404b4727)

- [News](https://resources.bioptimus.com/news?hsLang=en)
- [Case Studies](https://resources.bioptimus.com/case-studies?hsLang=en)
- [Blogs](https://resources.bioptimus.com/blogs?hsLang=en)
- [Videos, Podcasts & Webinars](https://resources.bioptimus.com/videos-podcasts-webinars?hsLang=en)
- [FAQs](https://resources.bioptimus.com/faqs?hsLang=en)

- Home
- Products
- Resources
- Company

[![Bioptimus logo\_Logo Black](https://resources.bioptimus.com/hs-fs/hubfs/Bioptimus%20logo_Logo%20Black.png?width=300&height=113&name=Bioptimus%20logo_Logo%20Black.png "Bioptimus logo_Logo Black")](http://www.bioptimus.com)

<https://www.facebook.com/> <https://www.twitter.com/> <https://www.instagram.com/> <https://podcasts.apple.com/> [mailto:contact@bioptimus.com](mailto:contact@bioptimus.com) <https://fr.linkedin.com/company/bioptimus>

Copyright © 2026, Bioptimus SAS